Search results for " Interruption"

showing 9 items of 9 documents

Does the Compliance to Intravesical BCG Differ between Common Clinical Practice and International Multicentric Trials?

2015

<b><i>Introduction:</i></b> The aim of this study was to analyze the reasons for intravesical BCG interruption in clinical practice. BCG for at least one year is advocated as the best regimen to treat high-risk non-muscle invasive bladder cancer (NMIBC). However, almost 50% of patients don't complete it. Toxicity accounts for 10% of dropouts in international trials. <b><i>Materials and Methods:</i></b> Patients with T1HG NMIBC undergoing 1-year BCG were enrolled in this study. BCG was administered for one year. Toxicity and causes of treatment interruption were recorded. <b><i>Results:</i></b> A total of 411 patients we…

AdultMalemedicine.medical_specialtyUrologyInternational CooperationAntineoplastic AgentsSettore MED/24 - UrologiaMedication AdherenceSocial lifeCohort StudiesRecurrenceInternal medicinemedicineHumansAgedBladder cancerbusiness.industryMiddle Agedmedicine.diseaseSurgeryClinical PracticeRegimenAdministration IntravesicalTreatment OutcomeUrinary Bladder NeoplasmsTreatment interruptionToxicityBCG VaccineDisease ProgressionIntravesical bcgPatient ComplianceFemalenon muscle invasive bladder cancer Bacillus Calmette Guèrin intravesical instillation immunotherapy compliance toxicityNeoplasm Recurrence LocalbusinessCohort studyUrologia internationalis
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Use of long acting injectable aripiprazole before and through pregnancy in bipolar disorder: a case report

2019

Abstract Background Long-acting injectable (LAI) antipsychotics for psychotic disorders provide advantages in treatment compliance, but data on their use in pregnancy are very limited. We present a clinical case of aripiprazole LAI use in pregnancy. Case presentation A 43-year-old woman diagnosed with bipolar disorder, with several relapses due to treatment interruption while trying to conceive. Finally, aripiprazole LAI treatment was planned by mutual agreement between doctor and the patient, who took aripiprazole LAI before and during pregnancy. She gave birth at 40 weeks to a 3500 g baby girl with no congenital malformations, who was healthy at 5 months after delivery. Conclusion As far …

AdultPediatricsmedicine.medical_specialtyTime FactorsBipolar disordermedicine.medical_treatmentvirusesAripiprazoleCase Report030226 pharmacology & pharmacyInjections IntramuscularAntipsychotic03 medical and health sciences0302 clinical medicineimmune system diseasesPregnancylcsh:RA1190-1270medicineHumansPharmacology (medical)Bipolar disorderAntipsychoticlcsh:Toxicology. PoisonsPharmacologyDosage FormsPregnancybusiness.industrylcsh:RM1-950Pregnancy Outcomevirus diseasesCongenital malformationsmedicine.diseasePregnancy ComplicationsLong actinglcsh:Therapeutics. PharmacologyTreatment interruptionLong-acting injectable aripiprazoleAripiprazoleFemaleClinical casebusinessmedicine.drugAntipsychotic AgentsFollow-Up StudiesBMC Pharmacology and Toxicology
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Intravesical mitoxantrone in superficial bladder tumours (Ta-T1)

1993

Abstract 36 patients with histologically proven grade G1–G2, Ta-T1 transitional cell carcinoma of the bladder were introduced, after transurethral resection (TUR), into a study of intravesical chemoprophylaxis with mitoxantrone (20 mg diluted in 50 ml). After a mean follow-up of 23 months, 16 (50%) patients showed a superficial recurrence with a mean recurrence rate of 0.56 per year. In 19 patients with recurring tumours the mean recurrence rate decreased from 1.65 to 0.58 per year. 9 patients (25.7%) suffered from a chemical cystitis that in 2 cases (5.7%) required treatment interruption.

Cancer Researchmedicine.medical_specialtymedicine.medical_treatmentUrologyResectionCystitismedicineHumansCarcinoma Transitional CellMitoxantroneChemotherapyUrinary bladderbusiness.industrymedicine.diseaseSurgeryChemical cystitisAdministration IntravesicalTransitional cell carcinomamedicine.anatomical_structureUrinary Bladder NeoplasmsOncologyTreatment interruptionChemoprophylaxisMitoxantroneNeoplasm Recurrence Localbusinessmedicine.drugEuropean Journal of Cancer
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About the journey. Stasis, chiasmus and interruptions A geography essay

2022

The journey is a very stimulating function to read the congeries of relationships that intersect and signify the bonds of men with places. A device that activates, in Geography, different heuristic perspectives. The first chapter then aims at being part of the epistemological debate on the function of journey intended as a complex action through which relationships between man and space are strengthened and the fundamental cognitive processes are activated. In particular, in the first chapter, we want to foster a consideration on the tripartite scan that has the terminal outcome in the journey: stasis, trigger, experience. The second chapter then follows some literary suggestions to try to …

Journey Stasis Chiasmus Interruption Border Migration PandemicSettore M-GGR/02 - Geografia Economico-PoliticaSettore M-GGR/01 - Geografia
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La perception des parcours d’études non linéaires par les recruteur·euse·s

2020

Employer’s hiring behavior is changing and educational qualifications alone are not enough to explain hiring of graduates. In France, more and more young people drop out and return to full-time study. Therefore, they gain different life experiences outside the sphere of work: travel abroad, period of employment, civic services, etc. Yet, there was little research on this topic in France. This study explores the relationship between atypical schooling pathways and labour market entry from the perspective of employers. On the basis of vignette study, we stimulated a hiring process with a sample of recruiters. A study delay (Master level) was a negative brand in applicants’ resumes if experien…

Parcours atypiqueReprise d'étudesvignette studyEmployeurInsertion professionnelle[SHS.EDU] Humanities and Social Sciences/Educationtemporary schooling interruptionatypical schooling pathwaysrecruiter’s perceptionPerceptionParcours d'étudesrecruiter's perceptionMarché du travail
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La cultura ci salverà? Processi di touristification a base culturale nel centro storico di Palermo

2023

Negli ultimi tre decenni la cultura ha avuto un ruolo chiave nella costruzione delle politiche urbane, divenendo uno strumento decisivo nella definizione delle strategie di sviluppo economico e nell’accesso alla competizione globale che caratterizzano l’attuale regime di neoliberismo urbano (Miles e Paddison 2005). Anche nel sud Europa la cosiddetta rigenerazione a base culturale ha rappresentato e continua ancora oggi a rappresentare una vera e propria ortodossia urbana, che trova nel turismo tanto una ragione di esistenza quanto un campo di attuazione. In particolare, negli ultimi anni i centri storici di molte città sudeuropee sono stati oggetto di trasformazioni profonde in cui pratiche…

Within this framework Palermo and its historic center are no exception. The epicenter of these processes is represented here by the Kalsa district which since the early 2000s has been placed at the center of a precise strategy of culturally-based renewal called to drive the city's tourist renaissance (Vinci 2008). The culmination of this path came in 2018 when Palermo was named the Italian capital of culture and chosen as the venue for Manifesta one of the most prestigious traveling biennales of contemporary art. However the exponential increase in tourist arrivals in the last three years came to a halt with the outbreak of the pandemic which showed with unprecedented evidence the contradictions of the development strategies pursued in the historic center and the marks they leave on the territories. While this sudden interruption seems to offer an opportunity to radically rethink urban and cultural policies and find new curbs to the conditions of overtourism in which the historic centers of South European cities and beyond find themselves it could also prove to be an accelerator of the dynamics of commodification of these spaces representing the revival of tourism an easy escape route in times of crisis. The objective of this contribution is to critically explore the urban and social transformations that have crossed the Kalsa district of Palermo from the 2000s to the present using qualitative and quantitative techniques (analysis of statistical data in-depth interviews critical discourse analysis ...) with particular reference to the role that culture has played in these processes. While it is impossible to prefigure post-pandemic scenarios we will examine documents and discourses that trace possible development directions for South European cities and their historic centers.Settore ICAR/21 - UrbanisticaSettore M-GGR/01 - Geografia
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Differential Effects of Interruptions and Distractions on Working Memory Processes in an ERP Study

2020

Interruptions (interfering stimuli to respond to) and distractions (interfering stimuli to be ignored) have been shown to negatively impact performance, particularly in tasks requiring working memory (WM). This study investigated how these two types of external interference affect task performance and attentional and WM processes as indexed by specific event-related potentials (ERPs) of the EEG. A Continuous Number Task (CNT) was applied, in which participants had to either decide whether the current number (condition without WM load) or the sum of the current and the preceding number (condition with WM load) was odd or even while responding to interlaced single letters (interruptions) or i…

external interferenceinterruptionexternal interference ; attention ; distraction ; EEG ; interruption ; working memoryEEGlcsh:Neurosciences. Biological psychiatry. Neuropsychiatrybehavioral disciplines and activitiespsychological phenomena and processesdistractionworking memorylcsh:RC321-571NeuroscienceOriginal ResearchattentionFrontiers in Human Neuroscience
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Clinical experience with retrievable vena cava filters: results of a prospective observational multicenter study

2005

Summary. Background: Retrievable inferior vena cava (IVC) filters offer the attractive possibility to be definitive or to be removed when they become unnecessary. Objective: The purpose of this study was to evaluate the efficacy and the likelihood to remove the retrievable IVC filter ALN. Methods: A total of 30 patients (13 males and 17 females, mean age 57 ± 15 years) underwent placement of ALN filters. Indications for implantation were acute venous thromboembolism (VTE) with a contraindication to anticoagulation in 26 cases (86%), primary prophylaxis after major trauma in two cases (7%) or before surgery in two patients with very high thromboembolic risk (7%). Results: The filter was succ…

medicine.medical_specialtyVena cava filtersbusiness.industryDeep veinRetrievable inferior vena cava filterHematologymedicine.diseaseThrombosisAsymptomaticInferior vena cavaSurgerymedicine.anatomical_structuremedicine.veinVena cava interruptionMedicineObservational studyRadiologymedicine.symptombusinessContraindicationVenous thromboembolismVenous thromboembolismJournal of Thrombosis and Haemostasis
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The Employer Perception of Non-linear Educational Pathways. A Vignette Study with French Employers

2018

International audience; We explore the relationship between educational pathways and labour market entry with vignette study. We stimulate a hiring process with a sample of recruiters and we analyze the role of schooling discontinuities in the screening of applicant resumes. Applicant may follow di fferent pathways: some of them are graduated on time, others face delay because they had a job or because they traveled abroad. Then, we analyze the determinants of employers' preferences with regressions: the likelihood to hire the candidate is used as dependent variable. We show that temporary schooling interruption has a negative effect on recruiters rating if applicant do not specify the reas…

vignette study[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/Educationtemporary schooling interruption[SHS.ECO] Humanities and Social Sciences/Economics and Finance[SHS.ECO]Humanities and Social Sciences/Economics and Financerecruiter's perceptionhealth care economics and organizations
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